If you love meat lover’s pizza, you’re going to love this easy casserole version. This Meat Lover’s Ground Beef Pizza Casserole combines tender penne pasta, seasoned ground beef, pizza sauce, pepperoni, and plenty of melted mozzarella cheese. It’s hearty, comforting, and incredibly easy to make.
Everything comes together in one casserole dish and bakes up bubbly, cheesy, and full of pizza flavor. It’s perfect for a weeknight dinner when you’re craving pizza but want something a little different.
Meat Lover’s Ground Beef Pizza Casserole
Description
This easy meat lover’s pizza casserole combines penne pasta, seasoned ground beef, pizza sauce, and pepperoni, all baked together with melted mozzarella cheese. It’s a simple and comforting dinner recipe that’s perfect for feeding the whole family.
Ingredients
Instructions
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Cook the penne pasta in salted boiling water until just al dente according to package instructions. Drain and add to an 8 by 8 greased casserole or baking dish. Add in 1/2 cup of pizza sauce and mix with the pasta. Spread about half a cup of mozzarella over the top. Set aside.
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Add the ground beef to a pan over medium high heat. Break it up and fry until cooked through and browned. Push to one side of the pan and add in the mushrooms. Stir and cook until they begin to change color and release water. Mix and push to one side again. Add in the onion and garlic. Stir and sauté until fragrant. Mix again. Add in the pizza sauce followed by the salt, pepper, Italian seasoning, and oregano. Mix until well combined.
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Add the ground beef mixture over the pasta in the baking dish. Sprinkle the remaining mozzarella over the top. Place the pepperoni over the cheese. Sprinkle the basil over. Bake for about 20 minutes in a 375 degree F preheated oven.
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Allow to cool for a few minutes. Serve and enjoy your Meat Lover’s Ground Beef Pizza Casserole!
Nutrition Facts
- Amount Per Serving
- Calories 520kcal
- % Daily Value *
- Total Fat 27g42%
- Sodium 780mg33%
- Total Carbohydrate 40g14%
- Dietary Fiber 3g12%
- Sugars 6g
- Protein 28g57%
* Percent Daily Values are based on a 2,000 calorie diet. Your daily value may be higher or lower depending on your calorie needs. Nutritional values are a within reason estimate and my vary depending on several factors.
Note
- You can easily add cooked bacon or sausage to make the casserole even more like a classic meat lover’s pizza.
- If you like vegetables, bell peppers or olives also work well in this recipe.
- Letting the casserole rest for a few minutes before serving helps it hold together better.

